Pediatric sickle cell disease and obstructive sleep apnea

Year: 2018 |Volume: 25 |Issue: 3 |Page: 183-187
Pediatric sickle cell disease and obstructive sleep apnea: A cross-sectional study in a tertiary pediatric center in Saudi Arabia

Wadha Alotaibi1,Safa Eltahir1,Mohmmed Rayis2,Khalid Al-Mobaireek1,Ayah Alsarheed1,Gawahir Mukhtar1,Jumageldi Jumayev3,Suhail Al-Saleh4
1Department of Pediatrics, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia
2Department of Hematology Oncology, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia
3Sleep disorders Center, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia
4Division of Respiratory Medicine, Hospital for Sick Children; Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada
Correspondence Address:
Dr. Wadha Alotaibi
Department of Pediatrics, King Fahad Medical City, P. O. Box: 59046, Riyadh 11525
Kingdom of Saudi Arabia
Source of Support:None,Conflict of Interest:None
Objective:The aim of the study was to evaluate snoring and obstructive sleep apnea (OSA) in Saudi children with sickle cell disease (SCD).Materials and Methods:This cross-sectional study was conducted among children with SCD attending a hematology clinic were recruited. Demographics, clinical data, and sleep questionnaires were collected and overnight polysomnographies performed.Results:Seventy children (31 of whom were females) with SCD were included in the study. Their median (interquartile) age was 9 (6.5, 11) years and their body mass indexz-score was −1.2 (−2.0, −0.4). Seventy-four percent of SCD patients snored and 32 (46%) had evidence of OSA (obstructive apnea-hypopnea index [OAHI] ≥2 events per hour of sleep), 13 of whom had moderate OSA (OAHI ≥5 and <10 events per hour of sleep) and 10 had severe OSA (OAHI ≥10 events per hour of sleep).Conclusion:Snoring and the proportion of OSA were high in children with SCD. This underlines the importance of screening for OSA in all children with SCD.


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