Liposuction does not improve cardiovascular risk factors

Question Does liposuction improve cardiovascular risk factorprofiles for obese women?

Synopsis The researchers identified 15 obese women, eight withnormal glucose tolerance (mean body mass index (BMI) = 35.1)and seven with abnormal glucose tolerance or type 2 diabetesmellitus (mean BMI = 39.9). Each had a series of metabolic parametersmeasured at baseline, and again after large volume liposuction.This was not a little nip and tuck—the average patienthad 7.05 kg (15.5 lbs) removed during the procedure. There wasno significant improvement in the cardiovascular risk factors(blood pressure, lipid levels, plasma glucose, plasma insulin)or on measures of inflammation after the liposuction. Thoughthe study was small, it was appropriately powered to find astatistically significant change in the outcomes reported.

Bottom line Liposuction of an average of 7 kg of abdominal fatdoes not result in an improvement in cardiovascular risk factors,including measures of inflammation and insulin resistance. Dietand exercise are better ideas.

Level of evidence 4 (see Caseseries

Klein S, Fontana L, Young VL, et al. Absence of an effect ofliposuction on insulin action and risk factors for coronaryheart disease. N Engl J Med 2004;350: 2549-57 [Abstract/Free Full Text].


well-baby visits for children up to two years old -0001-11-30
What is the optimal management for patients with acute low back pain in the primary care setting? -0001-11-30
Blood pressure control by home monitoring: meta-analysis of randomised trials -0001-11-30
Clinical effectiveness and cost-effectiveness of prehospital intravenous fluids in trauma patients -0001-11-30
Promotion of smoking cessation in developing countries - an evidence base -0001-11-30
Effective and ineffective interventions for infant colic -0001-11-30
Cough suppressants are ineffective in children -0001-11-30